David H. Perlmutter

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich et al. · Autophagy · 2012 · 4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

An Autophagy-Enhancing Drug Promotes Degradation of Mutant α ₁ -Antitrypsin Z and Reduces Hepatic Fibrosis

Tunda Hidvegi, Michael Ewing, Pamela Hale et al. · Science · 2010 · 598 citations

Medicine, Pharmacology, Pharmacotherapy +16

Chemical chaperones mediate increased secretion of mutant α1-antitrypsin (α1-AT) Z: A potential pharmacological strategy for prevention of liver injury and emphysema in α1-AT deficiency

Jon A. J. Burrows, Lauren K. Willis, David H. Perlmutter · Proceedings of the National Academy of Sciences · 2000 · 431 citations

Life Sciences, Biochemistry, Pharmacology +17

Intracellular Inclusions Containing Mutant α1-Antitrypsin Z Are Propagated in the Absence of Autophagic Activity

Takahiro Kamimoto, Shisako Shoji, Tunda Hidvegi et al. · Journal of Biological Chemistry · 2005 · 255 citations · Full text

Life Sciences, Genetics, Pathology +16

Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung.

David L. Haviland, R L McCoy, William Whitehead et al. · The Journal of Immunology · 1995 · 248 citations

Life Sciences, Cell Biology, Immunology +14