Michael Orth

Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

Jong‐Min Lee, Vanessa C. Wheeler, Michael J. Chao et al. · Cell · 2015 · 675 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Davina J. Hensman Moss, Antonio F. Pardiñas, Douglas R. Langbehn et al. · The Lancet Neurology · 2017 · 332 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY)

Erik van Duijn, David Craufurd, Anna A.M. Hubers et al. · Journal of Neurology Neurosurgery & Psychiatry · 2014 · 290 citations · Full text

Medicine, Neurology, Psychiatry +12

An exploratory double‐blind, randomized clinical trial with selisistat, a <scp>SirT1</scp> inhibitor, in patients with <scp>H</scp>untington's disease

Sigurd D. Süßmuth, Salman Haider, G. Bernhard Landwehrmeyer et al. · British Journal of Clinical Pharmacology · 2014 · 164 citations · Full text

Medicine, Neurology, Pharmacology +17

The HTT CAG-Expansion Mutation Determines Age at Death but Not Disease Duration in Huntington Disease

Jae Whan Keum, Aram Shin, Tammy Gillis et al. · The American Journal of Human Genetics · 2016 · 164 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13