Patricia López

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cells

Undine Lauf, Ben N. G. Giepmans, Patricia López et al. · Proceedings of the National Academy of Sciences · 2002 · 321 citations

Life Sciences, Cell Biology, Molecular Biology +17

Mutation and polymorphism spectrum of the GALNS gene in mucopolysaccharidosis IVA (Morquio A)

Shunji Tomatsu, Adriana M. Montaño, Tatsuo Nishioka et al. · Human Mutation · 2005 · 179 citations

Medicine, Genetics, Molecular Genetics +17

From Fragment Screening to In Vivo Efficacy: Optimization of a Series of 2-Aminoquinolines as Potent Inhibitors of Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1)

Yuan Cheng, Ted Judd, Michael D. Bartberger et al. · Journal of Medicinal Chemistry · 2011 · 141 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Expression of fluorescently tagged connexins: a novel approach to rescue function of oligomeric DsRed‐tagged proteins¹

Undine Lauf, Patricia López, Matthias M. Falk · FEBS Letters · 2001 · 86 citations

Life Sciences, Cell Biology, Molecular Biology +16