Concepedia

Raji Sundaramoorthi

RS

Statistics

Publications

25

Citations

2.9K

H-Index

19

Active since

1985

Affiliations

Ariadne Diagnostics (United States)(Current)

Oregon Health & Science University

Harvard University

Aridis Pharmaceuticals (United States)

Howard Hughes Medical Institute

Raji Sundaramoorthi is an author at Ariadne Diagnostics (United States) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

1985–2011

25

Publications

25

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

Thomas O’Hare, William C. Shakespeare, Xiaotian Zhu et al. · Cancer Cell · 2009 · 1.2K citations · Full text

, , +9

Discovery of 3-[2-(Imidazo[1,2-<i>b</i>]pyridazin-3-yl)ethynyl]-4-methyl-<i>N</i>-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant

Wei‐Sheng Huang, Chester A. Metcalf, Raji Sundaramoorthi et al. · Journal of Medicinal Chemistry · 2010 · 362 citations · Full text

, , +12

Expression and isolation of antimicrobial small molecules from soil DNA libraries.

I A MacNeil, Choi Lai Tiong, C Minor et al. · PubMed · 2001 · 213 citations

, , +17

Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML

Thomas O’Hare, Roy M. Pollock, Eric P. Stoffregen et al. · Blood · 2004 · 199 citations · Full text

, , +8

Structure-based design of an osteoclast-selective, nonpeptide Src homology 2 inhibitor with <i>in vivo</i> antiresorptive activity

William C. Shakespeare, Michael G. Yang, Regine S. Bohacek et al. · Proceedings of the National Academy of Sciences · 2000 · 133 citations · Full text

, , +17

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