Roberto R. Rosato

Oligonucleotide Aptamers: New Tools for Targeted Cancer Therapy

Hongguang Sun, Xun Zhu, Patrick Lu et al. · Molecular Therapy — Nucleic Acids · 2014 · 530 citations · Full text

Medicine, Molecular Biology, Oncology +17

The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.

Roberto R. Rosato, Jorge A. Almenara, Steven Grant · PubMed · 2003 · 470 citations

Medicine, Oncology, Pharmacology +17

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Fan Yao, Yalan Deng, Yang Zhao et al. · Nature Communications · 2021 · 337 citations · Full text

Medicine, Cancer Biology, Oncology +8

Simultaneous activation of the intrinsic and extrinsic pathways by histone deacetylase (HDAC) inhibitors and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) synergistically induces mitochondrial damage and apoptosis in human leukemia cells.

Roberto R. Rosato, Jorge A. Almenara, Yun Dai et al. · PubMed · 2003 · 230 citations

Life Sciences, Cell Biology, Pharmacology +17

β-Lactams Increase the Antibacterial Activity of Daptomycin against Clinical Methicillin-Resistant Staphylococcus aureus Strains and Prevent Selection of Daptomycin-Resistant Derivatives

Shrenik Mehta, Christopher R. Singh, Konrad Plata et al. · Antimicrobial Agents and Chemotherapy · 2012 · 143 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17