K Obata

Effects of Hydrostatic Pressure on Matrix Synthesis and Matrix Metalloproteinase Production in the Human Lumbar Intervertebral Disc

Tadashi Handa, Hirokazu Ishihara, Hiroshi Ohshima et al. · Spine · 1997 · 315 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +17

Excess of metalloproteases over tissue inhibitor of metalloprotease may contribute to cartilage degradation in osteoarthritis and rheumatoid arthritis.

Johanne Martel‐Pelletier, R. W. McCollum, Noboru Fujimoto et al. · PubMed · 1994 · 266 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +12

Tumor targeting of doxorubicin by anti-MT1-MMP antibody-modified PEG liposomes

Hiroto Hatakeyama, Hidetaka Akita, Emi Ishida et al. · International Journal of Pharmaceutics · 2007 · 167 citations

Pharmacy, Oncology, Pharmacology +14

Increased levels of stromelysin‐1 and tissue inhibitor of metalloproteinases–1 in sera from patients with rheumatoid arthritis

Yasuo Yoshihara, K Obata, Noboru Fujimot et al. · Arthritis & Rheumatism · 1995 · 163 citations

Medicine, Clinical Sciences, Internal Medicine +17

Production and Activation of Matrix Metalloproteinase-2 in Proliferative Diabetic Retinopathy

Kousuke Noda, Susumu Ishida, Makoto Inoue et al. · Investigative Ophthalmology & Visual Science · 2003 · 124 citations

Medicine, Ophthalmology, Pathology +14