Catherine A. Schaeffer

Inhibitors of HIV Nucleocapsid Protein Zinc Fingers as Candidates for the Treatment of AIDS

William G. Rice, Jeffrey G. Supko, Louis Malspeis et al. · Science · 1995 · 231 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds

William G. Rice, Catherine A. Schaeffer, Brad Harten et al. · Nature · 1993 · 201 citations

Life Sciences, Infectious Diseases, Molecular Biology +6

Induction of endonuclease-mediated apoptosis in tumor cells by C-nitroso-substituted ligands of poly(ADP-ribose) polymerase.

William G. Rice, Christopher D. Hillyer, Brad Harten et al. · Proceedings of the National Academy of Sciences · 1992 · 88 citations

Life Sciences, Molecular Biology, Pharmacology +17

Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins

William G. Rice, David C. Baker, Catherine A. Schaeffer et al. · Antimicrobial Agents and Chemotherapy · 1997 · 84 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +14

Evaluation of Selected Chemotypes in Coupled Cellular and Molecular Target-Based Screens Identifies Novel HIV-1 Zinc Finger Inhibitors

William G. Rice, Jim A. Turpin, Catherine A. Schaeffer et al. · Journal of Medicinal Chemistry · 1996 · 83 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14