Girija Krishnamurthy

Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1:  Design, Synthesis, and Preclinical Characterization

Hassan Elokdah, Magid Abou‐Gharbia, James K. Hennan et al. · Journal of Medicinal Chemistry · 2004 · 166 citations · Full text

Pharmaceutical Science, Antiparasitic Agent, Cardiovascular Pharmacology +20

Molecular Mechanism of Hepatitis C Virus Replicon Variants with Reduced Susceptibility to a Benzofuran Inhibitor, HCV-796

Anita Y. M. Howe, Huiming Cheng, S V Johann et al. · Antimicrobial Agents and Chemotherapy · 2008 · 105 citations · Full text

Viral Replication, Viral Polymerase Structure, Hepatitis C Virus +18

Potent α-Synuclein Aggregation Inhibitors, Identified by High-Throughput Screening, Mainly Target the Monomeric State

Martin Kurnik, Cagla Sahin, Camilla Andersen et al. · Cell chemical biology · 2018 · 85 citations

Neurodegenerative Diseases, Drug Target, Biochemistry +7

Parallel synthesis and biological evaluation of 5,6,7,8-tetrahydrobenzothieno[2,3-d]pyrimidin-4(3H)-one cytotoxic agents selective for p21-deficient cells

Lee D. Jennings, Scott L. Kincaid, Yanong D. Wang et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 75 citations

Medicinal Chemistry, P21-deficient Cells, Biochemistry +10

Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment

Scott C. Mayer, A. Banker, Frank Boschelli et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 67 citations · Full text

Medicinal Chemistry, Medicine, Isoquinolinedione Inhibitors +9