Brian C. Lewis

c-Myc transactivation of <i>LDH-A</i> : Implications for tumor metabolism and growth

Hyunsuk Shim, Christine Dolde, Brian C. Lewis et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +17

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

Win May, Mikhail L. Gishizky, Stephen L. Lessnick et al. · Proceedings of the National Academy of Sciences · 1993 · 577 citations

Medicine, Molecular Biology, Oncology +17

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

Win May, Stephen L. Lessnick, Benjamin S. Braun et al. · Molecular and Cellular Biology · 1993 · 498 citations · Full text

Medicine, Molecular Biology, Oncology +16

A unique glucose-dependent apoptotic pathway induced by c-Myc

Hyunsuk Shim, Yoon S. Chun, Brian C. Lewis et al. · Proceedings of the National Academy of Sciences · 1998 · 286 citations

Life Sciences, Cell Biology, Oncology +17

Sonic hedgehog acts at multiple stages during pancreatic tumorigenesis

Jennifer P. Morton, Michelle E. Mongeau, David S. Klimstra et al. · Proceedings of the National Academy of Sciences · 2007 · 222 citations

Medicine, Cancer Biology, Oncology +17