Xiaowen Shen

Homology-mediated end joining-based targeted integration using CRISPR/Cas9

Xuan Yao, Xing Wang, Xinde Hu et al. · Cell Research · 2017 · 342 citations · Full text

In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR–dCas9-activator transgenic mice

Haibo Zhou, Junlai Liu, Changyang Zhou et al. · Nature Neuroscience · 2018 · 274 citations

Transcriptional Regulation, Systems Biology, In Vivo Gene Therapy +12

Engineered CRISPR-OsCas12f1 and RhCas12f1 with robust activities and expanded target range for genome editing

Xiangfeng Kong, Hainan Zhang, Guoling Li et al. · Nature Communications · 2023 · 84 citations · Full text

Engineering, Biomolecular Tool, Molecular Biology +18

Production and characterization of homopolymer poly(3-hydroxyvalerate) (PHV) accumulated by wild type and recombinant Aeromonas hydrophila strain 4AK4

Xiaowen Shen, Yun Yang, Jian Jia et al. · Bioresource Technology · 2009 · 78 citations

Biomanufacturing, Engineering, Natural Polymer +11

CRISPR-free, programmable RNA pseudouridylation to suppress premature termination codons

Jinghui Song, Liting Dong, Hanxiao Sun et al. · Molecular Cell · 2022 · 76 citations · Full text

Programmable Rna Pseudouridylation, Molecular Biology, Genetic Engineering +4