Concepedia

Guizhen Zhou

GZ

10

Publications

281

Citations

10

H-Index

2021

Active since

Affiliations

Chinese Academy of Sciences(Current)

Shanghai Institute of Materia Medica

University of Chinese Academy of Sciences

Nanjing University of Chinese Medicine

ShanghaiTech University

Guizhen Zhou is an author at Chinese Academy of Sciences specializing in drug discovery, medicine, and pharmacology.

Top concepts

Publications per year

2021–2025

10

Publications

10

Discovery of the First-in-Class Agonist-Based SOS1 PROTACs Effective in Human Cancer Cells Harboring Various KRAS Mutations

Chuan Zhou, Zisheng Fan, Zehui Zhou et al. · Journal of Medicinal Chemistry · 2022 · 77 citations · Full text

Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers

Zehui Zhou, Guizhen Zhou, Chuan Zhou et al. · Journal of Medicinal Chemistry · 2023 · 36 citations · Full text

Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRAS<sup>G12D</sup>

Chuan Zhou, Zisheng Fan, Yuejiao Gu et al. · Journal of Medicinal Chemistry · 2024 · 35 citations · Full text

Ginkgetin Alleviates Inflammation and Senescence by Targeting STING

Yadan Liu, Jialin Ye, Zisheng Fan et al. · Advanced Science · 2024 · 27 citations · Full text

Design, Synthesis, and Bioevaluation of Pyrido[2,3-<i>d</i>]pyrimidin-7-ones as Potent SOS1 Inhibitors

Meiying Liu, Guizhen Zhou, Wenhong Su et al. · ACS Medicinal Chemistry Letters · 2023 · 25 citations · Full text

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