Yan‐Ni Shi

Modification and de novo design of non-ribosomal peptide synthetases using specific assembly points within condensation domains

Kenan A. J. Bozhüyük, Annabell Linck, Andreas Tietze et al. · Nature Chemistry · 2019 · 180 citations

Life Sciences, Biochemistry, Molecular Biology +11

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria

Yi‐Ming Shi, Merle Hirschmann, Yan‐Ni Shi et al. · Nature Chemistry · 2022 · 119 citations · Full text

Life Sciences, Biology, Microbiology +16

Evolution-inspired engineering of nonribosomal peptide synthetases

Kenan A. J. Bozhüyük, Leonard Präve, Carsten Kegler et al. · Science · 2024 · 88 citations · Full text

Life Sciences, Biochemistry, Biotechnology +16

Integrating genomics and metabolomics for scalable non-ribosomal peptide discovery

Bahar Behsaz, Edna Bode, Alexey Gurevich et al. · Nature Communications · 2021 · 74 citations · Full text

Life Sciences, Bioinformatics, Microbiology +17

Promoter Activation in Δ<i>hfq</i> Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing

Edna Bode, Antje K. Heinrich, Merle Hirschmann et al. · Angewandte Chemie International Edition · 2019 · 73 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14