Karen Yuan

An Activated ErbB3/NRG1 Autocrine Loop Supports In Vivo Proliferation in Ovarian Cancer Cells

Qing Sheng, Xinggang Liu, Eleanor Fleming et al. · Cancer Cell · 2010 · 230 citations · Full text

Oncology, Cell Regulation, Medicine +10

Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases

Xiaozhang Zheng, Nan Ji, Veronica A. Campbell et al. · Journal of Medicinal Chemistry · 2024 · 42 citations · Full text

Kt-474─a Potent, Immunodeficiencies, Immune Regulation +24

Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining

Jennifer Eccleston, Catherine T. Yan, Karen Yuan et al. · The Journal of Immunology · 2011 · 41 citations · Full text

Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma

Matthew M. Weiss, Xiaozhang Zheng, Nan Ji et al. · Journal of Medicinal Chemistry · 2024 · 31 citations · Full text

Hematological Malignancy, Lymphoid Neoplasia, Abc Dlbcl Tumors +13

Class Switch Recombination Efficiency and Junction Microhomology Patterns in Msh2-, Mlh1-, and Exo1-Deficient Mice Depend on the Presence of μ Switch Region Tandem Repeats

Jennifer Eccleston, Carol E. Schrader, Karen Yuan et al. · The Journal of Immunology · 2009 · 23 citations · Full text

Knockout Mouse, Smutr Region, Genome Instability +13