Eugene Y. Tan

Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome

Xin Gu, Jasminka Dragovic, Gloria C. Koo et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

KRYSTAL-2: A phase I/II trial of adagrasib (MRTX849) in combination with TNO155 in patients with advanced solid tumors with KRAS G12C mutation.

Joshua K. Sabari, Haeseong Park, Anthony W. Tolcher et al. · Journal of Clinical Oncology · 2021 · 53 citations

Medicine, Oncology, Pharmacology +17

Metabolism and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Humans

Sanjeev Kumar, Eugene Y. Tan, Georgy Hartmann et al. · Drug Metabolism and Disposition · 2009 · 35 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Pharmacokinetics, Metabolism, and Excretion of Anacetrapib, a Novel Inhibitor of the Cholesteryl Ester Transfer Protein, in Rats and Rhesus Monkeys

Eugene Y. Tan, Georgy Hartmann, Qing Chen et al. · Drug Metabolism and Disposition · 2009 · 31 citations

Pharmacy, Pharmacokinetics, Pharmacology +17