James D. Winkler

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Jing Lü, Yimin Qian, Martha Altieri et al. · Chemistry & Biology · 2015 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +6

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Kanak Raina, Jing Lü, Yimin Qian et al. · Proceedings of the National Academy of Sciences · 2016 · 827 citations · Full text

Medicine, Molecular Biology, Oncology +17

The codependence of angiogenesis and chronic inflammation

Jeffrey R. Jackson, Michael Seed, Charles H. Kircher et al. · The FASEB Journal · 1997 · 699 citations

Veterinary Medicine, Immunology, Cell Signaling +14

Biological Characterization of ARRY-142886 (AZD6244), a Potent, Highly Selective Mitogen-Activated Protein Kinase Kinase 1/2 Inhibitor

Tammie C. Yeh, Vivienne Marsh, Bryan A. Bernat et al. · Clinical Cancer Research · 2007 · 583 citations · Full text

Medicine, Oncology, Pharmacology +14

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Priya Chaturvedi, Wai K Eng, Yuan Zhu et al. · Oncogene · 1999 · 424 citations

Life Sciences, Cell Biology, Molecular Biology +15