Vanessa Martins

Phase I Clinical Trial of a Selective Inhibitor of CYP17, Abiraterone Acetate, Confirms That Castration-Resistant Prostate Cancer Commonly Remains Hormone Driven

Gerhardt Attard, Alison Reid, Timothy A. Yap et al. · Journal of Clinical Oncology · 2008 · 896 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Phase I Clinical Trial of the CYP17 Inhibitor Abiraterone Acetate Demonstrating Clinical Activity in Patients With Castration-Resistant Prostate Cancer Who Received Prior Ketoconazole Therapy

Charles J. Ryan, Matthew R. Smith, Lawrence Fong et al. · Journal of Clinical Oncology · 2010 · 395 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

AT13148 Is a Novel, Oral Multi-AGC Kinase Inhibitor with Potent Pharmacodynamic and Antitumor Activity

Timothy A. Yap, Mike I. Walton, Kyla M. Grimshaw et al. · Clinical Cancer Research · 2012 · 91 citations · Full text

Medicine, Oncology, Pharmacology +17