Concepedia

E. Tim O’Brien

ET

Statistics

Publications

8

Citations

1.2K

H-Index

8

Active since

1990

Affiliations

University of North Carolina at Chapel Hill(Current)

Duke University

Duke University Hospital

Duke Medical Center

E. Tim O’Brien is an author at University of North Carolina at Chapel Hill specializing in medicine, engineering, and extracellular matrix.

Top concepts

MedicineEngineeringCell BiologyMatrix BiologyMechanobiologyCell BiomechanicsExtracellular MatrixBiomedical EngineeringBiophysicsTumor Biology

Publications per year

1990–2015

8

Publications

8

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

Vinay Swaminathan, Karthikeyan Mythreye, E. Tim O’Brien et al. · Cancer Research · 2011 · 732 citations · Full text

Engineering, Mechanical Engineering, Cytoskeleton +30

HIF1α and HIF2α independently activate SRC to promote melanoma metastases

Sara C. Hanna, Bhavani Krishnan, Sean T. Bailey et al. · Journal of Clinical Investigation · 2013 · 144 citations · Full text

Cancer Research, Transcriptional Regulation, Oncology +14

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells

Caitlin Collins, Lukas D. Osborne, Christophe Guilluy et al. · Nature Communications · 2014 · 111 citations · Full text

Mechanobiology, Engineering, Mechanical Phenotype +15

Effects of magnesium on the dynamic instability of individual microtubules

E. Tim O’Brien, E. D. Salmon, R. A. Walker et al. · Biochemistry · 1990 · 82 citations

TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion

Lukas D. Osborne, George Z. Li, Tam How et al. · Molecular Biology of the Cell · 2014 · 60 citations · Full text

Tgf-β Regulates Larg, Cell Adhesion, Cytoskeleton +22

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