Joerg R. Weber

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Ludwig Kappos, Amit Bar‐Or, Bruce Cree et al. · The Lancet · 2018 · 896 citations

Neurological Disorder, Clinical Neurology, Clinical Trials +9

Lipoteichoic Acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus Activates Immune Cells via Toll-like Receptor (TLR)-2, Lipopolysaccharide-binding Protein (LBP), and CD14, whereas TLR-4 and MD-2 Are Not Involved

Nicolas W.J. Schröder, Siegfried Morath, Christian Alexander et al. · Journal of Biological Chemistry · 2003 · 630 citations · Full text

Pneumococcal pneumolysin and H2O2 mediate brain cell apoptosis during meningitis

Johann Braun, Jack Sublett, Dorette Freyer et al. · Journal of Clinical Investigation · 2002 · 309 citations · Full text

A Vicious Cycle Involving Release of Heat Shock Protein 60 from Injured Cells and Activation of Toll-Like Receptor 4 Mediates Neurodegeneration in the CNS

Seija Lehnardt, Eckart Schott, Thorsten Trimbuch et al. · Journal of Neuroscience · 2008 · 267 citations · Full text

Injured Cells, Similar Inflammatory Response, Immunology +18

Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia

Seija Lehnardt, Sabrina Lehmann, David Kaul et al. · Journal of Neuroimmunology · 2007 · 247 citations

Inflammation, Medicine, Immunology +13