Clare Duncan

TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway

Diane Moujalled, Alexandra Grubman, Karla Acevedo et al. · Human Molecular Genetics · 2017 · 81 citations · Full text

Reductive Stress, Downstream Nrf2 Antioxidant, Neurodegenerative Diseases +13

Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress

Diane Moujalled, Janine L. James, Sarah J. Parker et al. · PLoS ONE · 2013 · 56 citations · Full text

Kinase Inhibitors, Molecular Biology, Tdp-43 Cytosolic Accumulation +19

Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43

Diane Moujalled, Janine L. James, Shu Yang et al. · Human Molecular Genetics · 2014 · 51 citations

Molecular Biology, Cyclin-dependent Kinase 2, Signaling Pathway +16

Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes

Jeffrey R. Liddell, Šárka Lehtonen, Clare Duncan et al. · Journal of Neuroinflammation · 2016 · 51 citations · Full text

Neuroprotective Copper Bis(thiosemicarbazonato) Complexes Promote Neurite Elongation

Laura Bica, Jeffrey R. Liddell, Paul S. Donnelly et al. · PLoS ONE · 2014 · 46 citations · Full text

Medicinal Chemistry, Neurodegenerative Diseases, Alzheimer's Disease +12