Anthony M. Brumby

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

Anthony M. Brumby · The EMBO Journal · 2003 · 621 citations · Full text

Pattern Formation, Developmental Biology, Oncogenic Ras +10

An <i>in vivo</i> large-scale chemical screening platform using <i>Drosophila</i> for anti-cancer drug discovery

Lee Willoughby, Tanja Schlosser, Samuel A. Manning et al. · Disease Models & Mechanisms · 2012 · 133 citations · Full text

Drug Target, Hit Identification, Pyrimidine Biosynthesis +16

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

Karen Doggett, Felix Grusche, Helena E. Richardson et al. · BMC Developmental Biology · 2011 · 120 citations · Full text

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

Lukas E. Dow, Anthony M. Brumby, Rosa Muratore et al. · Oncogene · 2003 · 112 citations

Chromatin, Drosophila Tumour Suppressor, Functional Homologue +7

Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye

Nicola A. Grzeschik, Nancy Amin, Julie Secombe et al. · Developmental Biology · 2007 · 95 citations · Full text

Developmental Biology, Cell Division, Developmental Genetics +12