Anthony M. Brumby

scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila

Anthony M. Brumby, Helena E. Richardson · The EMBO Journal · 2003 · 630 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

An <i>in vivo</i> large-scale chemical screening platform using <i>Drosophila</i> for anti-cancer drug discovery

Lee Willoughby, Tanja Schlosser, Samuel A. Manning et al. · Disease Models & Mechanisms · 2012 · 134 citations · Full text

Medicine, Oncology, Pharmacokinetics +13

Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling

Karen Doggett, Felix Grusche, Helena E. Richardson et al. · BMC Developmental Biology · 2011 · 120 citations · Full text

Life Sciences, Cell Biology, Genetics +17

hScrib is a functional homologue of the Drosophila tumour suppressor Scribble

Lukas E. Dow, Anthony M. Brumby, Rosa Muratore et al. · Oncogene · 2003 · 112 citations

Life Sciences, Genetics, Molecular Biology +8

Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye

Nicola A. Grzeschik, Nancy Amin, Julie Secombe et al. · Developmental Biology · 2007 · 95 citations · Full text

Life Sciences, Developmental Biology, Genetics +13