Michiaki Tominaga

Characterization of a novel aquaretic agent, OPC‐31260, as an orally effective, nonpeptide vasopressin V₂ receptor antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Hiroshi Yamashita et al. · British Journal of Pharmacology · 1992 · 347 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

OPC-41061, a Highly Potent Human Vasopressin V2-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats

Yoshitaka Yamamura, Shigeki Nakamura, S. Itoh et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 332 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +12

OPC-21268, an Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Tomihiko Chihara et al. · Science · 1991 · 272 citations

Medicine, Pharmacology, Physiology +17

7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-41061): A potent, orally active nonpeptide arginine vasopressin V2 receptor antagonist

Kazumi Kondo, Hidenori Ogawa, Hiroshi Yamashita et al. · Bioorganic & Medicinal Chemistry · 1999 · 115 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Orally Active, Nonpeptide Vasopressin V₂ Receptor Antagonists:  A Novel Series of 1-[4-(Benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1<i>H</i>-benzazepines and Related Compounds

Hidenori Ogawa, Hiroshi Yamashita, Kazumi Kondo et al. · Journal of Medicinal Chemistry · 1996 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8