7-Chloro-5-hydroxy-1-[2-methyl-4-(2-methylbenzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-1-benzazepine (OPC-41061): A potent, orally active nonpeptide arginine vasopressin V2 receptor antagonist

Characterization of a novel aquaretic agent, OPC‐31260, as an orally effective, nonpeptide vasopressin V₂ receptor antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Hiroshi Yamashita et al. · British Journal of Pharmacology · 1992 · 347 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

OPC-41061, a Highly Potent Human Vasopressin V2-Receptor Antagonist: Pharmacological Profile and Aquaretic Effect by Single and Multiple Oral Dosing in Rats

Yoshitaka Yamamura, Shigeki Nakamura, S. Itoh et al. · Journal of Pharmacology and Experimental Therapeutics · 1998 · 332 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +12

OPC-21268, an Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Tomihiko Chihara et al. · Science · 1991 · 272 citations

Medicine, Pharmacology, Physiology +17

Characterization of SR 121463A, a highly potent and selective, orally active vasopressin V2 receptor antagonist.

C. Serradeil‐Le Gal, C Lacour, G Valette et al. · Journal of Clinical Investigation · 1996 · 249 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

5-Fluoro-2-methyl-<i>N</i>-[4-(5<i>H</i>-pyrrolo[2,1-<i>c</i>]- [1,4]benzodiazepin-10(11<i>H</i>)-ylcarbonyl)-3- chlorophenyl]benzamide (VPA-985):  An Orally Active Arginine Vasopressin Antagonist with Selectivity for V₂Receptors

J. Donald Albright, Marvin F. Reich, Efren G. Delos Santos et al. · Journal of Medicinal Chemistry · 1998 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7