Tomihiko Chihara

Characterization of a novel aquaretic agent, OPC‐31260, as an orally effective, nonpeptide vasopressin V₂ receptor antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Hiroshi Yamashita et al. · British Journal of Pharmacology · 1992 · 346 citations · Full text

OPC-21268, an Orally Effective, Nonpeptide Vasopressin V1 Receptor Antagonist

Yoshitaka Yamamura, Hidenori Ogawa, Tomihiko Chihara et al. · Science · 1991 · 272 citations

Hypertension, Heart Failure, Arginine Vasopressin +14

OPC-21268, a vasopressin V1 antagonist, produces hypotension in spontaneously hypertensive rats.

Yasuhiro Yamada, Y Yamamura, Tomihiko Chihara et al. · Hypertension · 1994 · 32 citations · Full text

Hypertension, Blood Pressure, Cerebral Vascular Regulation +19

Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihydro-2(1H)-quinolinones

Hidenori Ogawa, Yoshitaka Yamamura, Hisashi Miyamoto et al. · Journal of Medicinal Chemistry · 1993 · 29 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Chemical Biology +17

Possible involvement of pertussis toxin-sensitive GTP-binding protein(s) in c-fos expression during differentiation of 3T3-L1 fibroblasts to adipocytes

Takashi Uehara, Tomihiko Chihara, Yukiko Tokumitsu et al. · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · 1991 · 12 citations

Inflammation, Possible Involvement, Signal Transduction +12