John T. Barrett

A role for macroautophagy in protection against 4-hydroxytamoxifen–induced cell death and the development of antiestrogen resistance

Julia S. Samaddar, Virgil T. Gaddy, Jennifer Duplantier et al. · Molecular Cancer Therapeutics · 2008 · 189 citations

Mitophagy, Breast Oncology, Apoptosis +20

Autophagy facilitates the progression of ERα-positive breast cancer cells to antiestrogen resistance

Patricia V. Schoenlein, Sudharsan Periyasamy‐Thandavan, Julia S. Samaddar et al. · Autophagy · 2009 · 124 citations · Full text

Double minute chromosomes carrying the human multidrug resistance 1 and 2 genes are generated from the dimerization of submicroscopic circular DNAs in colchicine-selected KB carcinoma cells.

Patricia V. Schoenlein, Donglai Shen, John T. Barrett et al. · Molecular Biology of the Cell · 1992 · 70 citations

Gene Amplification, Cytogenetics, Genetics +20

Mifepristone Induces Growth Arrest, Caspase Activation, and Apoptosis of Estrogen Receptor-Expressing, Antiestrogen-Resistant Breast Cancer Cells

Virgil T. Gaddy, John T. Barrett, Jennifer N. Delk et al. · Clinical Cancer Research · 2004 · 69 citations

Radiation therapy depletes extrachromosomally amplified drug resistance genes and oncogenes from tumor cells via micronuclear capture of episomes and double minute chromosomes

Patricia V. Schoenlein, John T. Barrett, Anita S. Kulharya et al. · International Journal of Radiation Oncology*Biology*Physics · 2003 · 50 citations

Tumor Biology, Radiation Oncology, Radiation Medicine +11