Alison H. Varghese

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

David Cunningham, Dennis E. Danley, Kieran F. Geoghegan et al. · Nature Structural & Molecular Biology · 2007 · 434 citations

Familial Hypercholesterolemia, Molecular Physiology, Biochemistry +10

Immunohistochemical localization of PDE10A in the rat brain

Thomas Seeger, Brenda L. Bartlett, Timothy Coskran et al. · Brain Research · 2003 · 340 citations

Immunohistochemical Localization, Neurophysiology, Neuroanatomy +6

Pharmacologic Inhibition of Site 1 Protease Activity Inhibits Sterol Regulatory Element-Binding Protein Processing and Reduces Lipogenic Enzyme Gene Expression and Lipid Synthesis in Cultured Cells and Experimental Animals

Julie L. Hawkins, Michael Robbins, Laurie C. Warren et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 146 citations

Discovery of Cytotoxic Dolastatin 10 Analogues with N-Terminal Modifications

Andreas Maderna, Matthew Doroski, Chakrapani Subramanyam et al. · Journal of Medicinal Chemistry · 2014 · 130 citations

Nanotherapeutics, Lead Auristatin, Peptide Science +20

Aminopyrrolidineamide inhibitors of site-1 protease

Bruce A. Hay, Barbara Abrams, A Zumbrunn et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 87 citations · Full text

Aminopyrrolidineamide Inhibitors, Protein Chemistry, Biochemistry +3