Yunyun Yang

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Yun Xia, Yonghua Xie, Zhengsen Yu et al. · Cell · 2018 · 253 citations · Full text

Pharmacy, Immunology, Pharmacology +16

KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge

Zhongwei Mao, Hongying Xiao, Pan‐Pan Shen et al. · Cell Discovery · 2022 · 154 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy

Wei Zeng, Xiuqin Li, Yunyun Yang et al. · ACS Catalysis · 2022 · 144 citations

Life Sciences, Biochemistry, Biotechnology +17

A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated Vγ9Vδ2 T Cell Activation

Yunyun Yang, Liping Li, Linjie Yuan et al. · Immunity · 2019 · 132 citations · Full text

Life Sciences, Biochemistry, Immunology +12

Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells

Linjie Yuan, Xianqiang Ma, Yunyun Yang et al. · Nature · 2023 · 126 citations · Full text

Life Sciences, Immunology, Molecular Biology +13