Yunyun Yang

The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Yun Xia, Yonghua Xie, Zhengsen Yu et al. · Cell · 2018 · 241 citations · Full text

Vaccination, Druggable Target, Vaccine Development +11

KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge

Zhongwei Mao, Hongying Xiao, Pan‐Pan Shen et al. · Cell Discovery · 2022 · 137 citations · Full text

A Structural Change in Butyrophilin upon Phosphoantigen Binding Underlies Phosphoantigen-Mediated Vγ9Vδ2 T Cell Activation

Yunyun Yang, Liping Li, Linjie Yuan et al. · Immunity · 2019 · 130 citations · Full text

Molecular Immunology, Signal Transduction, Immune Cell Development +14

Substrate-Binding Mode of a Thermophilic PET Hydrolase and Engineering the Enzyme to Enhance the Hydrolytic Efficacy

Wei Zeng, Xiuqin Li, Yunyun Yang et al. · ACS Catalysis · 2022 · 129 citations

Crystal Structure, Engineering, Substrate-binding Mode +19

Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells

Linjie Yuan, Xianqiang Ma, Yunyun Yang et al. · Nature · 2023 · 111 citations · Full text