Shih‐Hsien Chuang

Discovery of Pyrrole−Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile

Chao‐Cheng Chiang, Yu‐Hsiang Lin, Shu Lin et al. · Journal of Medicinal Chemistry · 2010 · 59 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Bioorganic Chemistry +13

Discovery of 4-Aryl-<i>N</i>-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties

Ying-Shuan E. Lee, Shih‐Hsien Chuang, Lynn Y.L. Huang et al. · Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1

Lynn Y.L. Huang, Ying-Shuan Lee, Jiann‐Jyh Huang et al. · Journal of Experimental & Clinical Cancer Research · 2014 · 36 citations · Full text

Copper(I)-Catalyzed Nitrile-Addition/<i>N</i>-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6<i>H</i>-indolo[3,2-<i>c</i>]quinolin-6-ones as Potent Topoisomerase-I Inhibitors

Wen-Yun Hsueh, Ying-Shuan E. Lee, Min-Sian Huang et al. · Journal of Medicinal Chemistry · 2021 · 27 citations · Full text

Inhibition of Hec1 as a novel approach for treatment of primary liver cancer

Lynn Y.L. Huang, Chia‐Chi Chang, Ying-Shuan Lee et al. · Cancer Chemotherapy and Pharmacology · 2014 · 25 citations

Primary Liver Cancer, Oncology, Hepatology +11