Eduardo Justo Martínez

Integrating transcriptional and metabolite profiles to direct the engineering of lovastatin-producing fungal strains

Manor Askenazi, Edward M. Driggers, Douglas A. Holtzman et al. · Nature Biotechnology · 2003 · 244 citations

Lovastatin-producing Fungal Strains, Engineering, Biochemistry +10

Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743

Eduardo Justo Martínez, Takashi Owa, Stuart L. Schreiber et al. · Proceedings of the National Academy of Sciences · 1999 · 169 citations

A New, More Efficient, and Effective Process for the Synthesis of a Key Pentacyclic Intermediate for Production of Ecteinascidin and Phthalascidin Antitumor Agents

Eduardo Justo Martínez, E. J. Corey · Organic Letters · 2000 · 102 citations

Combinatorial Chemistry, Bioorganic Chemistry, Key Intermediate +17

Molecular Scaffolds. 2. Intramolecular Hydrogen Bonding in 1,2-Diaminoethane Diureas

James S. Nowick, Muna Abdi, Keith A. Bellamo et al. · Journal of the American Chemical Society · 1995 · 90 citations

Molecular Sciences, Engineering, Biochemistry +14

Antitumor activity- and gene expression-based profiling of ecteinascidin Et 743 and phthalascidin Pt 650

Eduardo Justo Martínez, E.J. Corey, Takashi Owa · Chemistry & Biology · 2001 · 88 citations · Full text

Tumor Biology, Medicine, Gene Expression-based Profiling +10