Kidney protection effects of dihydroquercetin on diabetic nephropathy through suppressing ROS and NLRP3 inflammasome

Tao Ding, Shaofei Wang, Xuyao Zhang, +9

Phytomedicine

NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis

Jingyun Luan, Xuyao Zhang, Shaofei Wang, +9

Frontiers in Immunology

Functional Comparison of Interferon‐α Subtypes Reveals Potent Hepatitis B Virus Suppression by a Concerted Action of Interferon‐α and Interferon‐γ Signaling

Jieliang Chen, Yaming Li, Fritz Lai, +16

Hepatology

Targeted Interleukin-22 Gene Delivery in the Liver by Polymetformin and Penetratin-Based Hybrid Nanoparticles to Treat Nonalcoholic Fatty Liver Disease

Wenjing Zai, Wei Chen, Zimei Wu, +9

ACS Applied Materials & Interfaces

Targeting PARP and autophagy evoked synergistic lethality in hepatocellular carcinoma

Wenjing Zai, Wei Chen, Yuxuan Han, +10

Carcinogenesis

Curdione Ameliorated Doxorubicin-Induced Cardiotoxicity Through Suppressing Oxidative Stress and Activating Nrf2/HO-1 Pathway

Zimei Wu, Wenjing Zai, Wei Chen, +3

Journal of Cardiovascular Pharmacology

Heart FailureChemoprevention StrategyLipid PeroxidationDox-induced Cell ApoptosisCell Death +21

Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy

Wenjing Zai, Wei Chen, Jingyun Luan, +6

Applied Microbiology and Biotechnology

Acetaminophen-induced Hepatic CytotoxicityMitophagyCell AutophagyHepatologyMedicine +10

Autophagy suppression potentiates the anti-glioblastoma effect of asparaginase <i>in vitro</i> and <i>in vivo</i>

Qicheng Chen, Li Ye, Jiajun Fan, +14

Oncotarget

MitophagyApoptosisCell DeathGliomaTumor Biology +14

In vivo hepatocellular expression of interleukin-22 using penetratin-based hybrid nanoparticles as potential anti-hepatitis therapeutics

Wei Chen, Jingyun Luan, Gang Wei, +11

Biomaterials

NanoparticlesNanomedicineEngineeringHepatologyVivo Hepatocellular Expression +12

GSDMD membrane pore is critical for IL-1β release and antagonizing IL-1β by hepatocyte-specific nanobiologics is a promising therapeutics for murine alcoholic steatohepatitis

Jingyun Luan, Wei Chen, Jiajun Fan, +9

Biomaterials

InflammationHepatologyIl-1β ReleaseMedicineLiver Physiology +10