Naoki Ishiguro

Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities

Sumio Ohtsuki, Olaf Schaefer, Hirotaka Kawakami et al. · Drug Metabolism and Disposition · 2011 · 433 citations

Medicine, Biochemistry, Pharmacology +16

The Use of Transporter Probe Drug Cocktails for the Assessment of Transporter-Based Drug–Drug Interactions in a Clinical Setting—Proposal of a Four Component Transporter Cocktail

Thomas Ebner, Naoki Ishiguro, Mitchell E. Taub · Journal of Pharmaceutical Sciences · 2015 · 68 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

The Effect of Autologous Fibrin Tissue Adhesive on Postoperative Cerebrospinal Fluid Leak in Spinal Cord Surgery: A Randomized Controlled Trial

Hiroshi Nakamura, Yukihiro Matsuyama, Hisatake Yoshihara et al. · Spine · 2005 · 64 citations

Medicine, Neurosurgery, Surgery +8

Reliability and Robustness of Simultaneous Absolute Quantification of Drug Transporters, Cytochrome P450 Enzymes, and Udp-Glucuronosyltransferases in Human Liver Tissue by Multiplexed MRM/Selected Reaction Monitoring Mode Tandem Mass Spectrometry with Nano-Liquid Chromatography

Atsushi Sakamoto, Takehisa Matsumaru, Naoki Ishiguro et al. · Journal of Pharmaceutical Sciences · 2011 · 59 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Quantification of Transporter and Receptor Proteins in Dog Brain Capillaries and Choroid Plexus: Relevance for the Distribution in Brain and CSF of Selected BCRP and P-gp Substrates

Clemens Braun, Atsushi Sakamoto, Holger Fuchs et al. · Molecular Pharmaceutics · 2017 · 58 citations

Medicine, Biochemistry, Pharmacology +17