Iain P. Hargreaves

Association between mitochondrial dysfunction and severity and outcome of septic shock

David Brealey, M. P. Brand, Iain P. Hargreaves et al. · The Lancet · 2002 · 1.5K citations

Veterinary Medicine, Cell Biology, Pathobiology +14

Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

Patrick J. Pollard, J.-J. Brière, Neyaz Alam et al. · Human Molecular Genetics · 2005 · 849 citations · Full text

Medicine, Genetics, Oncology +17

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

Kira M. Holmström, Liam Baird, Ying Zhang et al. · Biology Open · 2013 · 455 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

L. Miguel Martins, Alastair Morrison, Kristina Klupsch et al. · Molecular and Cellular Biology · 2004 · 397 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

Houman Ashrafian, Gábor Czibik, Mohamed Bellahcene et al. · Cell Metabolism · 2012 · 306 citations · Full text

Life Sciences, Biochemistry, Cardiology +17