Iain P. Hargreaves

Association between mitochondrial dysfunction and severity and outcome of septic shock

David Brealey, M. P. Brand, Iain P. Hargreaves et al. · The Lancet · 2002 · 1.5K citations

Cardiogenic Shock, Mitochondrial Function, Mitochondrial Dysfunction +8

Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations

Patrick J. Pollard, J.-J. Brière, Neyaz Alam et al. · Human Molecular Genetics · 2005 · 843 citations · Full text

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

Kira M. Holmström, Liam Baird, Ying Zhang et al. · Biology Open · 2013 · 445 citations · Full text

Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

L. Miguel Martins, Alastair Morrison, Kristina Klupsch et al. · Molecular and Cellular Biology · 2004 · 396 citations · Full text

Mitophagy, Neuropeptides, Apoptosis +19

Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway

Houman Ashrafian, Gábor Czibik, Mohamed Bellahcene et al. · Cell Metabolism · 2012 · 300 citations · Full text