Cloning of the Gene Containing Mutations that Cause PARK8-Linked Parkinson's Disease

Coro Paisán‐Ruíz, Shushant Jain, E. Whitney Evans, +17

Neuron

Neurodegenerative DiseasesGenetic DisorderParkinson DiseaseGeneticsGene Containing Mutations +7

Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism

David R. Williams, Rohan de Silva, Dominic Paviour, +6

Brain

Motor DysfunctionDistinct Clinical PhenotypesNeurological DisorderCorticobasal DegenerationClinical Neurology +16

Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms

Cathy Andorfer, Yvonne Kress, Marisol Espinoza, +5

Journal of Neurochemistry

Genetic variability in the regulation of gene expression in ten regions of the human brain

Adaikalavan Ramasamy, Daniah Trabzuni, Sebastian Guelfi, +11

Nature Neuroscience

NeurogenomicsBrain StructureNeurophysiologyTen RegionsGenetics +9

Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

Yaroslau Compta, Laura Parkkinen, Sean S. O’Sullivan, +9

Brain

Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome

David R. Williams, Janice L. Holton, Catherine Strand, +4

Brain

Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability

Charles Shaw‐Smith, Alan Pittman, Lionel Willatt, +16

Nature Genetics

ChromatinDevelopmental BiologyCytogeneticsGenetic DisorderGenetics +7

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration

Jonathan D. Rohrer, Tammaryn Lashley, Jonathan M. Schott, +18

Brain

NeuropsychologyClinical SymptomsCorticobasal DegenerationPathologyAlzheimer's Disease +20

Argyrophilic Grain Disease Is a Sporadic 4-Repeat Tauopathy

Takashi Togo, Naruhiko Sahara, Shu-Hui Yen, +6

Journal of Neuropathology & Experimental Neurology

PathologyAlzheimer's DiseaseDegenerative PathologyNeurologyBrain Pathology +17

The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts

Amanda Myers, Alan Pittman, Alice Zhao, +16

Neurobiology of Disease

Allelic VariantHaplotype DeterminationGenetic DisorderGeneticsPathology +5