Purified Group X Secretory Phospholipase A2 Induced Prominent Release of Arachidonic Acid from Human Myeloid Leukemia Cells

Kohji Hanasaki, Takashi Ono, Akihiko Saiga, +8

Journal of Biological Chemistry

Novel Antiarthritic Agents with 1,2-Isothiazolidine-1,1-dioxide (γ-Sultam) Skeleton: Cytokine Suppressive Dual Inhibitors of Cyclooxygenase-2 and 5-Lipoxygenase

Masanao Inagaki, Tatsuo Tsuri, Hirokuni Jyoyama, +13

Journal of Medicinal Chemistry

PharmacotherapyAntioxidant MoietyGamma-sultam SkeletonPharmaceutical ChemistryInflammatory Arthritis +15

Tetracycline analogues (doxycycline and COL‐3) induce caspase‐dependent and ‐independent apoptosis in human colon cancer cells

Toshinao Onoda, Takashi Ono, Dipok Kumar Dhar, +2

International Journal of Cancer

ApoptosisImmunologyCell DeathCancer BiologyTetracycline Analogues +14

Mouse Group X Secretory Phospholipase A2 Induces a Potent Release of Arachidonic Acid from Spleen Cells and Acts as a Ligand for the Phospholipase A2 Receptor

Yasuhide Morioka, Akihiko Saiga, Yasunori Yokota, +8

Archives of Biochemistry and Biophysics

InflammationPhospholipase A2 ReceptorAnti-inflammatoryMolecular PhysiologySignal Transduction +13

Doxycycline inhibits cell proliferation and invasive potential: combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer cells

Toshinao Onoda, Takashi Ono, Dipok Kumar Dhar, +3

Journal of Laboratory and Clinical Medicine

OncologyMedicinePathologyColorectal CancerDoxycycline Inhibits +6

Suppression of murine endotoxic shock by sPLA2 inhibitor, indoxam, through group IIA sPLA2-independent mechanisms

Yasunori Yokota, Kohji Hanasaki, Takashi Ono, +3

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

InflammationAnti-inflammatoryAllergyMurine Endotoxic ShockSpla2 Inhibitor +5

Group V and X secretory phospholipase A2s-induced modification of high-density lipoprotein linked to the reduction of its antiatherogenic functions

Yoshikazu Ishimoto, Katsutoshi Yamada, Shigenori Yamamoto, +3

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Signal TransductionHigh-density LipoproteinBiochemistryOxysterolMedicine +8

Are the anti-inflammatory effects of dexamethasone responsible for inhibition of the induction of enzymes involved in prostanoid formation in rat carrageenin-induced pleurisy?

Michiko Kawamura, Ko Hatanaka, Maki Saito, +5

European Journal of Pharmacology

InflammationAnti-inflammatoryMedicineRat Carrageenin-induced PleurisyLipid Peroxidation +8

Role of peroxisome proliferator‐activated receptor‐gamma (PPARγ) during liver regeneration in rats

Yoshio Yamamoto, Takashi Ono, Dipok Kumar Dhar, +4

Journal of Gastroenterology and Hepatology

Immunochemical relatedness between secretory phospholipase A2 and intracellular·phospholipase A2

Mitsuhiro Okamoto, Takashi Ono, Hiromasa Tojo, +1

Biochemical and Biophysical Research Communications

Protein SecretionSecretory Phospholipase A2ImmunologySecretory GranulesCellular Biochemistry +3