Hiroyuki Hasegawa

Tetrahydrobiopterin Uptake in Supplemental Administration: Elevation of Tissue Tetrahydrobiopterin in Mice Following Uptake of the Exogenously Oxidized Product 7,8-Dihydrobiopterin and Subsequent Reduction by an Anti-folate-Sensitive Process

Keiko Sawabe, Kazunori Wakasugi, Hiroyuki Hasegawa · Journal of Pharmacological Sciences · 2004 · 72 citations · Full text

Tetrahydrobiopterin Has a Glucose-Lowering Effect by Suppressing Hepatic Gluconeogenesis in an Endothelial Nitric Oxide Synthase–Dependent Manner in Diabetic Mice

Abudukadier Abulizi, Yoshihito Fujita, Akio Obara et al. · Diabetes · 2013 · 48 citations · Full text

Diabetic Mice, Enos Dimerization, Insulin Signaling +19

Studies on Biologically Active Pteridines: III. The Absolute Configuration at the C-6 Chiral Center of Tetrahydrobiopterin Cofactor and Related Compounds1

Sadao Matsuura, Takashi Sugimoto, Hiroyuki Hasegawa et al. · The Journal of Biochemistry · 1980 · 47 citations

Bioorganic Chemistry, Absolute Configuration, Biochemistry +13

Cellular uptake of sepiapterin and push–pull accumulation of tetrahydrobiopterin

Keiko Sawabe, Kazumasa Yamamoto, Yoshinori Harada et al. · Molecular Genetics and Metabolism · 2008 · 40 citations

Protein Secretion, Signal Transduction, Biochemistry +8

Membrane transport of sepiapterin and dihydrobiopterin by equilibrative nucleoside transporters: A plausible gateway for the salvage pathway of Tetrahydrobiopterin biosynthesis

Akiko Ohashi, Yuko Sugawara, Kaori Mamada et al. · Molecular Genetics and Metabolism · 2010 · 37 citations

Tetrahydrobiopterin Biosynthesis, Biosynthesis, Protein Secretion +8