Akio Obara

Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1

Masahito Ogura, Yasuhiko Nakamura, Daisuke Tanaka et al. · Biochemical and Biophysical Research Communications · 2010 · 119 citations

Biosynthesis, Aldo-keto Reductase, Cellular Enzymology +7

Tetrahydrobiopterin Has a Glucose-Lowering Effect by Suppressing Hepatic Gluconeogenesis in an Endothelial Nitric Oxide Synthase–Dependent Manner in Diabetic Mice

Abudukadier Abulizi, Yoshihito Fujita, Akio Obara et al. · Diabetes · 2013 · 48 citations · Full text

Diabetic Mice, Enos Dimerization, Insulin Signaling +19

Metformin suppresses hepatic gluconeogenesis and lowers fasting blood glucose levels through reactive nitrogen species in mice

Yoshihito Fujita, Masaya Hosokawa, Shimpei Fujimoto et al. · Diabetologia · 2010 · 39 citations · Full text

Hepatic Gluconeogenesis, Metabolic Syndrome, Biochemistry +12

Paragonimiasis Cases Recently Found among Immigrants in Japan

Akio Obara, Fukumi Nakamura‐Uchiyama, Kenji Hiromatsu et al. · Internal Medicine · 2004 · 36 citations · Full text

DEPTOR-related mTOR suppression is involved in metformin's anti-cancer action in human liver cancer cells

Akio Obara, Yoshihito Fujita, Abudukadier Abulizi et al. · Biochemical and Biophysical Research Communications · 2015 · 30 citations

Oncology, Medicine, Liver Physiology +8