Alfie T. Baker

The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

Konstantin Knoblich, Sara Cruz Migoni, Susan Siew et al. · PLoS Biology · 2018 · 103 citations · Full text

Life Sciences, Cell Biology, Immunology +17

BTN3A1 Discriminates γδ T Cell Phosphoantigens from Nonantigenic Small Molecules <i>via</i> a Conformational Sensor in Its B30.2 Domain

Mahboob Salim, Timothy J. Knowles, Alfie T. Baker et al. · ACS Chemical Biology · 2017 · 64 citations · Full text

Life Sciences, Biochemistry, Immunology +16

Synthesis and Biological Evaluation of (<i>E</i>)-4-Hydroxy-3-methylbut-2-enyl Phosphate (HMBP) Aryloxy Triester Phosphoramidate Prodrugs as Activators of Vγ9/Vδ2 T-Cell Immune Responses

Martin S. Davey, Roshni Malde, Rory C. Mykura et al. · Journal of Medicinal Chemistry · 2018 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma

Daniel Fowler, Marta Barisa, Alba Southern et al. · Science Translational Medicine · 2024 · 29 citations · Full text

Life Sciences, Immunology, Oncology +17

In Vitro Suppression of T Cell Proliferation Is a Conserved Function of Primary and Immortalized Human Cancer-Associated Fibroblasts

Mohammed H. Abuwarwar, Alfie T. Baker, Jeffrey Harding et al. · International Journal of Molecular Sciences · 2021 · 19 citations · Full text

Medicine, Cancer Biology, Oncology +14