WNT signaling underlies the pathogenesis of neuropathic pain in rodents

Yankai Zhang, Zhi‐Jiang Huang, Su Liu, +3

Journal of Clinical Investigation

Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease

So Hyun Park, Ciaran M. Lee, Daniel P. Dever, +9

Nucleic Acids Research

Wnt/Ryk signaling contributes to neuropathic pain by regulating sensory neuron excitability and spinal synaptic plasticity in rats

Su Liu, Yuepeng Liu, Zhi‐Jiang Huang, +4

Pain

Pain DisordersPain MedicineSynaptic TransmissionNeuropathic PainMolecular Pain +22

Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells

M. Kyle Cromer, Joab Camarena, Renata M. Martin, +20

Nature Medicine

Progenitor CellsMedicineGeneticsHematologyBlood Cell +7

Reopening of ATP-sensitive potassium channels reduces neuropathic pain and regulates astroglial gap junctions in the rat spinal cord

Xuefeng Wu, Wentao Liu, Yuepeng Liu, +3

Pain

Pain MedicineSynaptic TransmissionNeuropathic PainMolecular PainPeripheral Nerve +25

Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells

Yankai Zhang, Alireza Paikari, Pavel Sumazin, +5

Blood

Chronic compression or acute dissociation of dorsal root ganglion induces cAMP-dependent neuronal hyperexcitability through activation of PAR2

Zhi‐Jiang Huang, Haochuan Li, Ashley A. Cowan, +3

Pain

Chronic CompressionSynaptic TransmissionNeuropathic PainMolecular PainNeurotransmission +21

p53 Nongenotoxic Activation and mTORC1 Inhibition Lead to Effective Combination for Neuroblastoma Therapy

Myrthala Moreno‐Smith, Anna Lakoma, Zaowen Chen, +14

Clinical Cancer Research

ViVo

Yeshuang Zhu, Yuntao Wang, Chun Yu, +6

Natural Language ProcessingMultimodal LlmEngineeringInformation RetrievalCorpus Linguistics +13

A signature of 24 aging‑related gene pairs predict overall survival in gastric cancer

Yankai Zhang, Yichao Yan, Ning Ning, +2

BioMedical Engineering OnLine