Steven D. Shapiro

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Thiennu H. Vu, J. Michael Shipley, Gabriele Bergers et al. · Cell · 1998 · 1.7K citations · Full text

Angiogenesis, Bone Morphogenic Protein, Pathology +10

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

R. Dean Hautamaki, Dale K. Kobayashi, Robert M. Senior et al. · Science · 1997 · 1.5K citations

A randomized, controlled trial of protocol-directed versus physician-directed weaning from mechanical ventilation

Marin H. Kollef, Steven D. Shapiro, Patricia Silver et al. · Critical Care Medicine · 1997 · 813 citations

Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens et al. · Nature Medicine · 1999 · 788 citations

Cardiomyopathy, Heart Failure, Cardiovascular Disease +11

Neutrophil elastase–mediated degradation of IRS-1 accelerates lung tumor growth

A. McGarry Houghton, Danuta M Rzymkiewicz, Hongbin Ji et al. · Nature Medicine · 2010 · 724 citations · Full text

Lung Inflammation, Tumor Growth, Medicine +5