Concepedia

Gregory Hughes

GH

Statistics

Publications

31

Citations

3.8K

H-Index

20

Active since

1982

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Merck Canada Inc. (Canada)

University of Toronto

St. John's University

Codexis (United States)

Gregory Hughes is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in chemistry, medicinal chemistry, and pharmacy.

Publications per year

1982–2022

31

Publications

31

Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture

Christopher K. Savile, Jacob M. Janey, Emily C. Mundorff et al. · Science · 2010 · 1.7K citations

Natural Sciences, Biotechnology, Chemistry +16

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 631 citations

Engineering, Biotechnology, Pharmaceutical Biotechnology +17

Catalytic Enantioselective Conjugate Reduction of Lactones and Lactams

Gregory Hughes, Masanari Kimura, Stephen L. Buchwald · Journal of the American Chemical Society · 2003 · 293 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Development of an Immobilized Transaminase Capable of Operating in Organic Solvent

Matthew D. Truppo, Hallena R. Strotman, Gregory Hughes · ChemCatChem · 2012 · 143 citations

Life Sciences, Biochemistry, Biotechnology +14

Palladium-Catalyzed Cross-Coupling Reactions of Pyridylboronic Acids with Heteroaryl Halides Bearing a Primary Amine Group: Synthesis of Highly Substituted Bipyridines and Pyrazinopyridines

Amy E. Thompson, Gregory Hughes, Andrei S. Batsanov et al. · The Journal of Organic Chemistry · 2004 · 107 citations · Full text

Natural Sciences, Chemistry, Catalysis +14

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