Mary Fitzgerald

Alveolar macrophage-mediated elastolysis: roles of matrix metalloproteinases, cysteine, and serine proteases

Richard Russell, Andrew J. Thorley, Sarah V. Culpitt et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2002 · 286 citations

Medicine, Biochemistry, Immunology +15

Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85‐8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases

Franz von Nussbaum, Volkhart M.‐J. Li, Swen Allerheiligen et al. · ChemMedChem · 2015 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Inhibition of antigen-induced contraction of guinea-pig airways by a leukotriene synthesis inhibitor, BAY x1005

Phillip J. Gardiner, Nigel J. Cuthbert, Hilary P. Francis et al. · European Journal of Pharmacology · 1994 · 19 citations

Life Sciences, Immunology, Pharmacology +11

A phase 2 study to evaluate the safety, efficacy and pharmacokinetics of DP2 antagonist GB001 and to explore biomarkers of airway inflammation in mild‐to‐moderate asthma

Héctor Ortega, Mary Fitzgerald, Kartik Raghupathi et al. · Clinical & Experimental Allergy · 2019 · 17 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +14

Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma

Gabriele Matschiner, Mary Fitzgerald, Ulrich Moebius et al. · Journal of Allergy and Clinical Immunology · 2022 · 17 citations · Full text

Pharmacy, Immunology, Pharmacology +16