Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells

Lan N. Truong, Yongjiang Li, Linda Shi, +6

Proceedings of the National Academy of Sciences

Short End ResectionDna DamageDna Double-strand BreaksGeneticsMolecular Biology +19

Retinal Nerve Fiber Layer Imaging with Spectral-Domain Optical Coherence Tomography

Christopher Kai-Shun Leung, Shi Lam, Robert N. Weinreb, +7

Ophthalmology

PhotonicsEngineeringRetinaOphthalmologyOptical Properties +6

CtIP Maintains Stability at Common Fragile Sites and Inverted Repeats by End Resection-Independent Endonuclease Activity

Hailong Wang, Yongjiang Li, Lan N. Truong, +12

Molecular Cell

Genome InstabilityNatural SciencesEndocytic PathwayMolecular BiologyDna Replication +7

Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation

Jennifer L. Johnson, Mahalakshmi Ramadass, Jing He, +7

Journal of Biological Chemistry

Impairment of chaperone‐mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosis

Gennaro Napolitano, Jennifer L. Johnson, Jing He, +5

EMBO Molecular Medicine

Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

Jinzhong Zhang, Jennifer L. Johnson, Jing He, +10

Journal of Biological Chemistry

Cell AutophagySignal TransductionNatural SciencesAutophagyRab7 Effector Rilp +8

Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction

Xi Liang, Yu Ding, Y Zhang, +6

Cell Death and Disease

Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane

Jennifer L. Johnson, Jing He, Mahalakshmi Ramadass, +4

Journal of Biological Chemistry

Signal TransductionRab11-binding ProteinPlasma MembraneCell SignalingNatural Sciences +9

Effects of gambogic acid on the activation of caspase-3 and downregulation of SIRT1 in RPMI-8226 multiple myeloma cells via the accumulation of ROS

Lijing Yang, Yan Chen, Jing He, +4

Oncology Letters

Rad50 Zinc Hook Is Important for the Mre11 Complex to Bind Chromosomal DNA Double-stranded Breaks and Initiate Various DNA Damage Responses

Jing He, Linda Shi, Lan N. Truong, +7

Journal of Biological Chemistry

ChromatinGenome InstabilityChromatin RemodelingMre11 ComplexNatural Sciences +8