Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation

Jennifer L. Johnson, Mahalakshmi Ramadass, Jing He, +7

Journal of Biological Chemistry

Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A

Jinzhong Zhang, Jennifer L. Johnson, Jing He, +10

Journal of Biological Chemistry

Cell AutophagySignal TransductionNatural SciencesAutophagyRab7 Effector Rilp +8

Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane

Jennifer L. Johnson, Jing He, Mahalakshmi Ramadass, +4

Journal of Biological Chemistry

Signal TransductionRab11-binding ProteinPlasma MembraneCell SignalingNatural Sciences +9

MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane

Angela R.M. Kurz, Monika Pruenster, Ina Rohwedder, +16

Journal of Clinical Investigation

Immune Cell MigrationImmunologyPathologyExtracellular MicrovesiclesCellular Physiology +18

Neutrophil Recruitment to the Lung in Both C5a- and CXCL1-Induced Alveolitis Is Impaired in Vitamin D–Binding Protein–Deficient Mice

Glenda Trujillo, David M. Habiel, Lingyin Ge, +3

The Journal of Immunology

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyPulmonary Alveolar Proteinosis +20

Identification of the gC1qR sites for the HIV-1 viral envelope protein gp41 and the HCV core protein: Implications in viral-specific pathogenesis and therapy

Lina Pednekar, Alisa Valentino, Yan Ji, +9

Molecular Immunology

Viral-specific PathogenesisHuman RetrovirusImmunologyAntiviral ResponseVirology +4

Sustained Activation of Toll-Like Receptor 9 Induces an Invasive Phenotype in Lung Fibroblasts

Varvara Kirillov, Jonathan T. Siler, Mahalakshmi Ramadass, +6

American Journal Of Pathology

InflammationToll-like ReceptorsFibrosisToll-like Receptor 9Inflammatory Lung Disease +11

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses

Jing He, Jennifer L. Johnson, Jlenia Monfregola, +5

Molecular Biology of the Cell

Late Endosomal MaturationMolecular RegulationImmunologyCytoskeletonCellular Physiology +18

Soluble gC1qR Is an Autocrine Signal That Induces B1R Expression on Endothelial Cells

Berhane Ghebrehiwet, Yan Ji, Alisa Valentino, +8

The Journal of Immunology

Increased Neutrophil Secretion Induced by NLRP3 Mutation Links the Inflammasome to Azurophilic Granule Exocytosis

Jennifer L. Johnson, Mahalakshmi Ramadass, Ariela Haimovich, +4

Frontiers in Cellular and Infection Microbiology