Accelerated Blood Clearance Phenomenon Upon Repeated Injection of PEG-modified PLA-nanoparticles

Tsutomu Ishihara, Miho Takeda, Haruka Sakamoto, +15

Pharmaceutical Research

NanoparticlesNanomedicineEngineeringNanomaterialsNanobiotechnology +5

Assessment of response to cancer therapy using fluorine-18-fluorodeoxyglucose and positron emission tomography.

Y Ichiya, Yasuo Kuwabara, Masami Otsuka, +5

PubMed

Cancer TherapyOncologic ImagingPathologyPositron Emission TomographyOncology +15

Synthetic studies on tabtoxin. Synthesis of a naturally occuring inhibitor of glutamine synthetase, tabtoxinine-β-lactam, and analogues

Jack E. Baldwin, Masami Otsuka, Philip M. Wallace

Tetrahedron

BiochemistrySynthetic StudiesMedicineDrug DevelopmentPharmacology +5

Total synthesis of deglyco-bleomycin A2

TOMOHISA TAKITA, Yōji Umezawa, Sei-ichi Saito, +7

Tetrahedron Letters

PharmacologyNatural Product SynthesisBiosynthesisTotal Synthesis

A molecular modeling study of inhibitors of nuclear factor kappa-B (p50) – DNA binding

Vineet Pande, Rakesh Kumar Sharma, Jun‐ichiro Inoue, +2

Journal of Computer-Aided Molecular Design

Molecular PharmacologyMolecular Modeling StudyDna BindingEngineeringMolecular Biology +7

A novel inhibitor of farnesyltransferase with a zinc site recognition moiety and a farnesyl group

Ayumi Tanaka, Mohamed O. Radwan, Akiyuki Hamasaki, +10

Bioorganic & Medicinal Chemistry Letters

Novel InhibitorBioorganic ChemistryBiochemistryNatural SciencesMolecular Biology +6

Stereoselective synthesis of (2s,3s,4r)-4-amino-3-hydroxy-2-methyl-pentanoic acid, an amino acid constituent of bleomycin, by aldold condensation)

Masatoshi Narita, Masami Otsuka, Susumu Kobayashi, +6

Tetrahedron Letters

EngineeringAmino Acid ConstituentOrganic ChemistryAldold CondensationStereoselective Synthesis +5

Screening for inducers of apoptosis in apoptosis-resistant human carcinoma cells

Kazuo Umezawa, Kumi Nakazawa, Yuki Uchihata, +1

Advances in Enzyme Regulation

Tumor BiologyChemoprevention StrategyMedicineApoptosisCell Death +7

Zinc-mediated binding of a low-molecular-weight stabilizer of the host anti-viral factor apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G

Mohamed O. Radwan, Sachiko Sonoda, Tomohiko Ejima, +5

Bioorganic & Medicinal Chemistry

Low-molecular-weight StabilizerViral ReplicationMolecular VirologyBiochemistryNatural Sciences +5

Synthesis of a naturally occurring inhibitor of glutamine synthetase, tabtoxinene-β-lactam

Jack E. Baldwin, Masami Otsuka, Philip M. Wallace

Journal of the Chemical Society Chemical Communications

ChemistryPharmaceutical ChemistrySpectra-structure CorrelationMolecular PharmacologyP. M. Wallace +16