David W. Griggs

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

Neil C. Henderson, Thomas D. Arnold, Yoshio Katamura et al. · Nature Medicine · 2013 · 851 citations · Full text

Inflammation, Core Molecular Pathway, Fibrosis +12

Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS‐4 and ADAMTS‐5

Ruo-Hua Song, Micky D. Tortorella, Anne‐Marie Malfait et al. · Arthritis & Rheumatism · 2007 · 400 citations

A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo.

V. Wayne Engleman, G. Allen Nickols, F. Patrick Ross et al. · Journal of Clinical Investigation · 1997 · 287 citations · Full text

Sclerostin, Bone Resorption, Orthopaedic Surgery +13

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

Carlos M. Minutti, Rucha V. Modak, Felicity Macdonald et al. · Immunity · 2019 · 209 citations · Full text

A novel CYR61-triggered ‘CYR61-αvβ3 integrin loop’ regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway

Javier A. Menéndez, Luciano Vellón, Inderjit Mehmi et al. · Oncogene · 2004 · 153 citations

Signal Transduction, Signaling Pathway, Erk1/erk2 Mapk +11