Roy J. Vaz

Characterization of HERG potassium channel inhibition using CoMSiA 3D QSAR and homology modeling approaches

Robert A. Pearlstein, Roy J. Vaz, Jiesheng Kang et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 220 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A crowdsourcing evaluation of the NIH chemical probes

Tudor I. Oprea, Cristian Bologa, Scott Boyer et al. · Nature Chemical Biology · 2009 · 112 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

Effects of MTX-23, a Novel PROTAC of Androgen Receptor Splice Variant-7 and Androgen Receptor, on CRPC Resistant to Second-Line Antiandrogen Therapy

Geun Taek Lee, Naoya Nagaya, Jenny Desantis et al. · Molecular Cancer Therapeutics · 2020 · 92 citations

Medicine, Oncology, Pharmacology +17

Predictive models for hERG potassium channel blockers

Giovanni Cianchetta, Yi Li, Jiesheng Kang et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 83 citations

Medicine, Cardiology, Pharmacology +14

A Pharmacophore Hypothesis for P-Glycoprotein Substrate Recognition Using GRIND-Based 3D-QSAR

Giovanni Cianchetta, Robert W. Singleton, Meng Zhang et al. · Journal of Medicinal Chemistry · 2005 · 82 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17