Wen‐Hsing Lin

Protein Kinase Inhibitor Design by Targeting the Asp-Phe-Gly (DFG) Motif: The Role of the DFG Motif in the Design of Epidermal Growth Factor Receptor Inhibitors

Yi-Hui Peng, Hui-Yi Shiao, Chih‐Hsiang Tu et al. · Journal of Medicinal Chemistry · 2013 · 135 citations · Full text

Drug Target, Medicinal Chemistry, Signaling Pathway +18

Design and Synthesis of Tetrahydropyridothieno[2,3-<i>d</i>]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side Chain Chirality and Michael Acceptor Group for Maximal Potency

Chia-Hsien Wu, Mohane Selvaraj Coumar, Chang-Ying Chu et al. · Journal of Medicinal Chemistry · 2010 · 109 citations · Full text

Kinase Inhibitors, Molecular Biology, Side Chain Chirality +20

Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes

Wen‐Hsing Lin · Human Molecular Genetics · 2001 · 83 citations · Full text

Genetics, Genetic Epidemiology, Human Polymorphism +19

Homology modeling of DFG-in FMS-like tyrosine kinase 3 (FLT3) and structure-based virtual screening for inhibitor identification

Yi-Yu Ke, Vivek Kumar Singh, Mohane Selvaraj Coumar et al. · Scientific Reports · 2015 · 81 citations · Full text

Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity

Sailu Sarvagalla, Vivek Kumar Singh, Yi-Yu Ke et al. · Journal of Computer-Aided Molecular Design · 2014 · 77 citations

Drug Target, Hit Identification, Biochemistry +11