Chia-Hsien Wu

Design and Synthesis of Tetrahydropyridothieno[2,3-<i>d</i>]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side Chain Chirality and Michael Acceptor Group for Maximal Potency

Chia-Hsien Wu, Mohane Selvaraj Coumar, Chang-Ying Chu et al. · Journal of Medicinal Chemistry · 2010 · 109 citations · Full text

Kinase Inhibitors, Molecular Biology, Side Chain Chirality +20

Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents–A drug repurposing strategy

Chia-Hsien Wu, Li-Yuan Bai, Ming-Hsui Tsai et al. · Scientific Reports · 2016 · 87 citations · Full text

PKC-β as a therapeutic target in CLL: PKC inhibitor AEB071 demonstrates preclinical activity in CLL

Dalia El‐Gamal, Katie Williams, Taylor D. LaFollette et al. · Blood · 2014 · 51 citations · Full text

Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response

Thitinun Anusornvongchai, Masaomi Nangaku, Tzu‐Ming Jao et al. · Kidney International · 2018 · 36 citations · Full text

Chronic Kidney Damage, Lipid Peroxidation, Cell Death +24