Phase I Escalating-Dose Trial of CAR-T Therapy Targeting CEA+ Metastatic Colorectal Cancers

Chengcheng Zhang, Zhe Wang, Zhi Yang, +20

Molecular Therapy

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma

Lin Zhang, Gang Huang, Xiaowu Li, +9

BMC Cancer

MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest

Yanmin Xu, X Y Feng, Leina Ma, +8

Cancer Letters

OncologyOncogenic AgentMedicineCell Cycle ArrestCell Biology +6

MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways

Yanmin Xu, Ji Huang, Leina Ma, +7

Cancer Letters

Carcinoma CellsMedicineCell BiologySmall RnaMicrorna-122 Confers +6

Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

Chungang Liu, Limei Liu, Xuejiao Chen, +10

PLoS ONE

Epigenetic ChangeDna MethylationPathologyCancer BiologyEpigenetics +16

Expression of miR-122 mediated by adenoviral vector induces apoptosis and cell cycle arrest of cancer cells.

Leina Ma, Jia Liu, Junjie Shen, +6

Cancer Biology & Therapy

IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer

Chao Yao, Li Su, Juanjuan Shan, +11

Stem Cells

From value co-creation to value co-destruction? The case of dockless bike sharing in China

Juelin Yin, Lixian Qian, Junjie Shen

Transportation Research Part D Transport and Environment

EconomicsSustainable DevelopmentBusinessEconomic AnalysisSharing Economy +6

Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells

Junyu Xiang, Ni Zhang, Hui Sun, +16

Gastroenterology

MedicineLiver PhysiologyMef2d RegulationHepatocellular Carcinoma CellsCell Death +9

Overexpression of the Transcription Factor MEF2D in Hepatocellular Carcinoma Sustains Malignant Character by Suppressing G2–M Transition Genes

Leina Ma, Jia Liu, Limei Liu, +13

Cancer Research

PathologyG2–m Transition GenesCancer BiologyTumor BiologyTranscriptional Regulation +15