Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

Juanjuan Shan, Junjie Shen, Limei Liu, +15

Hepatology

MicroRNA-122 sensitizes HCC cancer cells to adriamycin and vincristine through modulating expression of MDR and inducing cell cycle arrest

Yanmin Xu, X Y Feng, Leina Ma, +8

Cancer Letters

OncologyOncogenic AgentMedicineCell Cycle ArrestCell Biology +6

MicroRNA-122 confers sorafenib resistance to hepatocellular carcinoma cells by targeting IGF-1R to regulate RAS/RAF/ERK signaling pathways

Yanmin Xu, Ji Huang, Leina Ma, +7

Cancer Letters

Carcinoma CellsMedicineCell BiologySmall RnaMicrorna-122 Confers +6

Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

Chungang Liu, Limei Liu, Xuejiao Chen, +10

PLoS ONE

Epigenetic ChangeDna MethylationPathologyCancer BiologyEpigenetics +16

Sox9 regulates self‐renewal and tumorigenicity by promoting symmetrical cell division of cancer stem cells in hepatocellular carcinoma

Chungang Liu, Limei Liu, Xuejiao Chen, +8

Hepatology

Blockade of Wnt Signaling Inhibits Angiogenesis and Tumor Growth in Hepatocellular Carcinoma

Jie Hu, Aiwen Dong, Verónica Fernández-Ruiz, +4

Cancer Research

PathologyCell DeathCancer BiologyTumor BiologySignaling Pathway +16

IGF/STAT3/NANOG/Slug Signaling Axis Simultaneously Controls Epithelial-Mesenchymal Transition and Stemness Maintenance in Colorectal Cancer

Chao Yao, Li Su, Juanjuan Shan, +11

Stem Cells

LSD1 Stimulates Cancer-Associated Fibroblasts to Drive Notch3-Dependent Self-Renewal of Liver Cancer Stem–like Cells

Chungang Liu, Limei Liu, Xuejiao Chen, +6

Cancer Research

Disruption of SIRT7 Increases the Efficacy of Checkpoint Inhibitor via MEF2D Regulation of Programmed Cell Death 1 Ligand 1 in Hepatocellular Carcinoma Cells

Junyu Xiang, Ni Zhang, Hui Sun, +16

Gastroenterology

MedicineLiver PhysiologyMef2d RegulationHepatocellular Carcinoma CellsCell Death +9

SIRT1‐mediated transcriptional regulation of SOX2 is important for self‐renewal of liver cancer stem cells

Limei Liu, Chungang Liu, Qianzhen Zhang, +12

Hepatology