Daisuke Yasuda

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

Tetsuya Saito, Yoshinobu Ichimura, Keiko Taguchi et al. · Nature Communications · 2016 · 372 citations · Full text

Medicine, Molecular Biology, Oncology +17

Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity

Daisuke Yasuda, Mao Nakajima, Akihiro Yuasa et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 43 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +15

Inhibitors of the protein–protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line

Daisuke Yasuda, Tomoyuki Ohe, Kyôko Takahashi et al. · Free Radical Research · 2020 · 35 citations

Medicine, Oncology, Pharmacology +17

Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor

Daisuke Yasuda, Akihiro Yuasa, Rika Obata et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Antioxidant activities of 5-hydroxyoxindole and its 3-hydroxy-3-phenacyl derivatives: The suppression of lipid peroxidation and intracellular oxidative stress

Daisuke Yasuda, Kyôko Takahashi, Tomoyuki Ohe et al. · Bioorganic & Medicinal Chemistry · 2013 · 25 citations

Life Sciences, Biochemistry, Pharmacology +17